KD and Bmax determinations for [3H]Ro 15-1788 and [3H]indiplon in rat frontal cortex and cerebellar membrane homogenates
Values for KD and Bmax are the mean ± S.E.M. of at least three independent experiments performed in duplicate.
3H Label | Tissue | KD | Bmax |
|---|---|---|---|
| nM | pmol / mg protein | ||
| Ro 15-1788 | Cortex | 2.13 ± 0.09 | 5.08 ± 0.37 |
| Cerebellum | 1.65 ± 0.13 | 2.30 ± 0.06 | |
| Indiplon | Cortex | 1.01 ± 0.23 | 2.58 ± 0.45 |
|
| Cerebellum | 0.53 ± 0.03 | 1.16 ± 0.08 |