TABLE 5

Distribution of CYP2A13 variations in human lung samples used for mRNA analysis The 16 human lung samples that were used for allele-specific quantification of relative CYP2A13 mRNA levels were further analyzed for additional CYP2A13 variations in the range of -2 kilobases to 3′-UTR. The -729C > T SNP and the ACC insertion between nucleotides 1634 and 1635 (in exon 3) were not detected in any of the DNA samples, whereas the 1757A > G (in intron 3, or I3) and 7520C > G (in 3′-UTR) SNPs were heterozygous in all 16 samples. The -2000C > G, -1638G > T, and -886T > C variations have not been reported previously.