Relative mRNA levels of P450s and POR in rat livers and adipose tissues
Relative mRNA levels in arbitrary units were calculated by dividing P450 or POR mRNA levels by RPS9 mRNA levels determined by real-time RT-PCR as described under Materials and Methods. Data are means ± S.E.M. (n = 3).
Gene | Relative mRNA Level | ||||
|---|---|---|---|---|---|
| Liver | WAT | WAT/Liver Ratio | |||
| CYP1A1 | 0.068 ± 0.007 | 0.029 ± 0.002 | 0.43 | ||
| CYP1A2 | 198 ± 23 | 0.095 ± 0.074 | 0.00048 | ||
| CYP1B1 | 0.016 ± 0.002 | 1.22 ± 0.18 | 76 | ||
| CYP2B1 | 2.6 ± 0.8 | 0.26 ± 0.06 | 0.10 | ||
| CYP2B2 | 78 ± 13 | 0.093 ± 0.077 | 0.0012 | ||
| CYP2E1 | 150 ± 16 | 0.30 ± 0.21 | 0.0020 | ||
| CYP3A1 | 2280 ± 140 | 4.9 ± 4.6 | 0.0021 | ||
| CYP3A2 | 1320 ± 330 | 0.64 ± 0.56 | 0.00048 | ||
| OR | 58 ± 4 | 98 ± 25 | 1.7 | ||
WAT, white adipose tissue.