Parameter | Group | Time | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Baseline | T0 | T60 | T120 | T180 | T240 | |||||||
pH† | Placebo*** | 7.53 ± 0.02 | 7.50 ± 0.02 | 7.33 ± 0.03 | 7.31 ± 0.05 | 7.31 ± 0.05 | 7.29 ± 0.06 | |||||
BM§§§ | 7.52 ± 0.01 | 7.53 ± 0.01 | 7.39 ± 0.03 | 7.36 ± 0.04 | 7.34 ± 0.04 | 7.33 ± 0.05 | ||||||
PaO2/FiO2, mm Hg | Placebo*** | 531 ± 37 | 505 ± 30 | 235 ± 52 | 207 ± 31 | 232 ± 45 | 196 ± 51 | |||||
BM§§§ | 459 ± 38 | 467 ± 44 | 319 ± 69 | 289 ± 51 | 213 ± 35 | 242 ± 32 | ||||||
PaCO2, mm Hg | Placebo*** | 33.2 ± 0.8 | 35.2 ± 0.8 | 56.8 ± 4.9 | 58.5 ± 6.1 | 58.7 ± 5.8 | 64 ± 8.5 | |||||
| BM§§§ | 33.6 ± 0.4 | 32.5 ± 1.5 | 49.1 ± 3.5 | 47.1 ± 2.9 | 51.6 ± 3.9 | 51.6 ± 4.1 |