TABLE 1

Baseline cystometric values for the three study groups

The three study groups are intact and SCI cats studied with 8-OH-DPAT (Intact-DPAT and SCI-DPAT, respectively), and SCI cats studied with GR-46611 (SCI-GR). Bladder mass values for intact cats were obtained from 15 cats of the same age and body mass, which were used in other studies after this study was completed. All values are mean ± S.E.M.


Group

Threshold Volume

Micturition Volume

Residual Volume

Bladder Capacity

Bladder Pressure

Bladder Mass
ml ml mm Hg g
Intact-DPAT 4.1 ± 1.1 1.6 ± 0.4 3.3 ± 1.1 4.9 ± 1.0 22.1 ± 1.8 2.7 ± 0.2
SCI-DPAT 8.6 ± 1.8 1.4 ± 0.5 41.2 ± 21.6 42.5 ± 21.6 24.8 ± 2.3 6.7 ± 1.1
SCI-GR
6.0 ± 2.0
1.2 ± 0.2
7.0 ± 3.1
8.3 ± 3.1
33.8 ± 6.1
5.3 ± 0.5