Effects of drug treatment on body weight
Rats were treated for 3 weeks with vehicle (peanut oil; 0.5 ml/rat/day i.p.), prednisolone, or NCX-1015 (0.69, 1.38, or 6.90 μmol/kg/day i.p. for either steroid). Data are values of body weight (grams) and are reported as mean ± S.E.M. of 10 rats per group.
Experimental Group | Basal | Day 7 | Day 14 | Day 21 |
|---|---|---|---|---|
| Vehicle | 189 ± 3 | 191 ± 3 | 207 ± 3 | 223 ± 3 |
| Pred 0.69 | 188 ± 3 | 195 ± 2 | 209 ± 3 | 220 ± 4 |
| Pred 1.38 | 186 ± 2 | 195 ± 3 | 207 ± 2 | 221 ± 4 |
| Pred 6.90 | 195 ± 2 | 194 ± 3 | 208 ± 3 | 224 ± 3 |
| NCX-1015, 0.69 | 186 ± 2 | 197 ± 4 | 203 ± 3 | 228 ± 2 |
| NCX-1015, 1.38 | 190 ± 4 | 196 ± 2 | 202 ± 3 | 225 ± 3 |
| NCX-1015, 6.90 | 191 ± 2 | 197 ± 2 | 206 ± 3 | 224 ± 2 |