Expression level of B1R in the CNS of transgenic rat lines
Saturation binding analysis using either [3H]DALK or [35S]compound A was performed on membrane protein homogenates prepared from either whole brain or spinal cord.
Data are presented mean ± standard error.
Line | B1R | Kd DALK |
|---|---|---|
| fmole mg prot | nM | |
| 4 Het | 39 ± 4.2 (n = 18) | 0.17 ± 0.043 |
| 4 Hom | 84 ± 8.0 (n = 9) | 0.18 ± 0.032 |
| 14 | 4 (n = 1) | 0.24 |
| 15 | 7 (n = 1) | 0.19 |
| 23 | 8.1 ± 5.9 (n = 3) | 0.31 ± .079 |
Het, heterozygous; Hom, homozygous.