TABLE 2

The effect of a single administration of LPSs from B. fragilis, Y. enterocolitica, and C. jejuni (1 mg/kg i.p.) on acidified ASA (150 mg/kg i.g.)-induced gastric lesions and the accompanying changes in GBF Results are means ± S.E.M. of six examinations on six rats. The asterisk indicates a significant change in value compared with that obtained with vehicle or LPS alone.


Type of Test

Mean Lesion Area

GBF
mm2 % control
Vehicle (saline) 74 ± 11 58 ± 6
B. fragilis-LPS 54 ± 8* 69 ± 4*
Y. enterocolitica-LPS 48 ± 5* 73 ± 5*
C. jejuni-LPS
52 ± 7*
70 ± 3*