Influence of a unilateral 6-OHDA lesion of the substantia nigra pars compacta upon dialysis levels of monoamines and acetylcholine in the ipsilateral compared with contralateral striatum
Intact | 6-OHDA-Lesioned | ||
|---|---|---|---|
| pg/20-μl sample | |||
| DA | 5.96 ± 1.08 | 0.28 ± 0.09* | |
| NA | 0.10 ± 0.02 | 0.08 ± 0.02 | |
| 5-HT | 1.07 ± 0.24 | 1.05 ± 0.32 | |
| ACh | 1.34 ± 0.35 | 2.57 ± 0.34* | |
↵* Significance of differences between contralateral (intact) and ipsilateral (lesioned) striatum in paired Student's t test. P < 0.05