A comparison of the cell depth, C-fibre threshold, and predrug neuronal responses to electrical and natural stimuli in naive, carageenan, and SNL rats
Data for the electrical-evoked responses are expressed as the mean number of action potentials (APs) evoked by a train of 16 electrical stimuli at 3 times the threshold for C-fibres. Data for natural stimuli are expressed as the number of APs evoked during the 10-s period for which the stimulus was applied.
Naive | Carrageenan | SNL | |
|---|---|---|---|
| Cell depth (μm) | 670 ± 27 | 674 ± 38 | 613 ± 49 |
| C-fibre threshold (mA) | 2.4 ± 0.2 | 2.2 ± 0.2 | 2.3 ± 0.2 |
| Electrically evoked response (APs) | |||
| Aβ-fibre evoked response | 96 ± 9 | 104 ± 11 | 88 ± 9 |
| Aδ-fibre evoked response | 70 ± 12 | 75 ± 7 | 94 ± 12 |
| C-fibre evoked response | 395 ± 48 | 376 ± 29 | 314 ± 54 |
| Wind-up | 252 ± 71 | 204 ± 20 | 196 ± 57 |
| Naturally evoked response (APs) | |||
| Brush | 605 ± 72 | 623 ± 43 | 594 ± 64 |
| Heat | 632 ± 85 | 648 ± 61 | 535 ± 77 |
| von Frey 9g | 202 ± 49 | 216 ± 25 | 174 ± 35 |
| von Frey 75g | 657 ± 90 | 706 ± 68 | 610 ± 90 |