Hemodynamic parameters in rats submitted to isoprenaline (400 mg/kg) and potassium canrenoate (20 mg/kg/day)
Group | HR | SAP | DAP | MAP | LVEDP | dP/dt max | dP/dt min | ||
|---|---|---|---|---|---|---|---|---|---|
| min −1 | mm Hg | mm Hg/s | |||||||
| Control, n = 10 | 405 ± 12 | 148 ± 5 | 120 ± 3 | 134 ± 4 | 0.6 ± 1.3 | 8542 ± 459 | 8452 ± 357 | ||
| Control + PC, n = 11 | 365 ± 17 | 147 ± 8 | 121 ± 6 | 134 ± 6 | 3.8 ± 2.7 | 7542 ± 780 | 6538 ± 491 | ||
| ISO 400, n = 14 | 412 ± 16 | 146 ± 7 | 120 ± 6 | 134 ± 6 | 2.2 ± 2.4 | 6954 ± 558 | 6463 ± 500 | ||
| ISO 400 + PC, n = 9 | 367 ± 12 | 144 ± 11 | 118 ± 10 | 132 ± 11 | 1.2 ± 1.8 | 7264 ± 428 | 5620 ± 283 | ||
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| p < 0.05a | ||
Results are expressed as mean ± S.E.M.
HR, heart rate; SAP, systolic aortic pressure; DAP, diastolic aortic pressure; MAP, mean aortic pressure; LVEDP, left ventricular end-diastolic pressure; dP/dt max, positive-derived pressure; dP/dt min, negative-derived pressure.
↵ a Control + PC group versus ISO 400 + PC group.