TABLE 1

Antioxidant activity of flurbiprofen and derivatives The ability of the test compounds at concentrations of 1 to 300 μM to scavenge a stable free radical (DPPH) was assessed in vitro. The EC50 represents the concentration of the test compound that scavenged half of the free radical.


Compound

Antioxidant Activity (EC50)
μM
Ascorbic acid 40.1
Flurbiprofen >300
NCX-2216 >300
Ferulic acid 83.2
NCX-2057 103.4
NCX-2226
>300