TABLE 1

Mean responses per second (±S.E.M.) in CB1 knockout and wild-type mice after administration of the vehicle for cannabinoid and noncannabinoid compounds


Compound

Wild Type

Wild Type

Knockout

Knockout
Mean (±S.E.M.) N Mean (±S.E.M.) N
Δ9-THC 0.49 (0.05) 12 0.36 (0.03) 10
Methanandamide 0.56 (0.05) 10 0.37 (0.02) 9
O-1812 0.56 (0.07) 9 0.37 (0.06) 7
Morphine 0.62 (0.07) 12 0.40 (0.07) 6
Diazepam 0.50 (0.06) 12 0.49 (0.04) 5
Ethanol
0.68 (0.04)
10
0.46 (0.06)
8