TABLE 1

Body weight (BW) and uterus weights of female rats from experiment 1: sham-operated controls, untreated OVX rats, E20-treated OVX rats, and E100-treated OVX rats; and experiment 2: untreated OVX rats, P-treated OVX rats and E20 and P (E/P)-treated OVX rats

Weight gain (grams) is the difference between body weight (grams) on the day of surgery and final body weight (grams). Weights are expressed as mean ± S.E.M.




BW at Surgery

Final BW

Weight Gain

Uterus Weight

Uterus Weight/BW
g mg
Experiment 1
Sham-operated 266 ± 5 283 ± 7†† 17 ± 4 398 ± 31 1.40 ± 0.10
OVX 290 ± 6 370 ± 10†† 81 ± 8** 154 ± 17** 0.43 ± 0.06**
E20 269 ± 10 294 ± 15† 25 ± 7 423 ± 21 1.45 ± 0.07
E100 277 ± 7 279 ± 6 3 ± 4* 476 ± 22 1.71 ± 0.10*
Experiment 2
OVX 279 ± 4 354 ± 9† 75 ± 8 150 ± 16 0.44 ± 0.05
P 262 ± 6 344 ± 13† 82 ± 9 141 ± 8 0.41 ± 0.03
E/P
276 ± 5
272 ± 4
−4 ± 4*
537 ± 24*
1.97 ± 0.08*
  • *p < 0.05, **p < 0.001 compared with sham-operated rats for experiment 1, and compared with untreated OVX rats for experiment 2.

    p < 0.05, ††p < 0.001 compared with body weight at the time of surgery in the same group.