Plasma concentration of HMR 1402
Animal | Dose (i.v.) | Plasma Level | Result |
|---|---|---|---|
| μg/ml | |||
| 1a | 2 μg/kg/min | 0.504 | VF |
| 1b | 4 μg/kg/min | 1.246 | No arrhythmias |
| 2 | 4 μg/kg/min | 1.190 | No arrhythmias |
| 3 | 4 μg/kg/min | 1.275 | No arrhythmias |
| 4 | 4 μg/kg/min | No sample | No arrhythmias |
| 5 | 3.0 mg/kg | 2.283 | No arrhythmias |
| 6 | 3.0 mg/kg | 1.502 | No arrhythmias |
| 7 | 3.0 mg/kg | 5.336 | No arrhythmias |
| 8 | 3.0 mg/kg | 0.394 | VF |