Effects of ANP, DNP, and mini-ANP on spontaneous basal lipolysis on isolated human fat cells
Values are expressed in percent variation of spontaneous basal lipolysis (0.185 ± 0.052 μmol glycerol/100 mg lipid/60 min) evaluated by glycerol concentration in the incubation medium. Values are means ± S.E.M. of five separate experiments.
log [Concentration] | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| M | |||||||||
| 10 | 9 | 8 | 7 | 6 | |||||
| ANP | 63.2 ± 18* | 125. ± 32* | 228 ± 126* | 289 ± 103* | 295 ± 93* | ||||
| DNP | 194 ± 15* | 244 ± 43* | 293 ± 63* | 331 ± 61* | 322 ± 70* | ||||
| Mini-ANP | 58 ± 32* | 92 ± 38* | 298 ± 107 | 304 ± 78* | 280 ± 90* | ||||
↵* Significant when compared with basal lipolysis (P < 0.05).