TABLE 3

Comparisons of CYP2C9 diclofenac 4-hydroxylase metabolic activity


Data Source

Sample Size

Median Age

Median-Specific Activitya

Specific Activity Rangea
yr pmol / min / mg pmol / min / mg
Current study >5 mo to 18 yr 61 4.9 628 60-1996
Yasar et al. (2001) 11 NA 1555 217-4781
BD Gentestb
12
47
2515
1020-3970