TABLE 1

Effect of inhibition of carbon monoxide generation with intranucleus tractus solitarii administration of zinc protoporphyrin IX (ZnPPIX) on the cardiovascular effects of the metabotropic glutamate receptor agonists

	Control			ZnPPIX (1 nmol)
	ΔMBP	ΔHR	ΔMBP	ΔHR
	mm Hg	beats/min	mm Hg	beats/min
DHPG	−33±2	−49±7	−29±3	−39±7
APDC	−43±3	−71±5	−6±3^a	−8±4^a
l-AP4	−41±4	−78±10	−8±2^a	−28±9^a

↵ a Significantly different from corresponding control response (n = 10), P < 0.05.