TABLE 3

IC₅₀ values of various diuretics for organic anion uptake mediated by hOAT1 and rOAT1

S₂ hOAT1 was incubated in a solution containing either 5 μM [¹⁴C]PAH in the absence or presence of various concentrations of diuretics for 2 min at 37°C. Each value represents the mean ± S.E. of eight monolayers from two separate experiments.