Development of neuroproteins in control brain regions
Values are expressed in relative units (see Materials and Methods) and are shown for males and females combined because of the absence of sex interactions with age or region. Data for PN30 were compiled from the two control groups, those receiving vehicle injections on PN2–5 and on PN11–14, but comparisons of the effects of terbutaline were conducted only with the appropriately matched control cohort. For each neuroprotein, ANOVA indicates significant differences attributable to age and region (p < 0.0001).
Age | Region | GFAP | NF68 |
|---|---|---|---|
| PN6 | Midbrain + brainstem | 9.2 ± 0.3 | 47 ± 2 |
| Forebrain | 4.8 ± 0.2 | 15.4 ± 0.2 | |
| Cerebellum | 13 ± 1 | 34 ± 1 | |
| PN15 | Midbrain + brainstem | 91 ± 3 | 86 ± 3 |
| Forebrain | 40 ± 2 | 41 ± 1 | |
| Cerebellum | 85 ± 4 | 39 ± 1 | |
| PN30 | Midbrain | 31 ± 1 | 79 ± 3 |
| Brainstem | 72 ± 3 | 131 ± 3 | |
| Cerebral cortex | 24 ± 1 | 59 ± 2 | |
| Hippocampus | 61 ± 2 | 50 ± 2 | |
| Striatum | 21 ± 1 | 84 ± 2 | |
|
| Cerebellum | 98 ± 7 | 56 ± 3 |