Autoradiography of [3H]AFM and [3H]DASB binding in the brain of SERT mutant mice
The data are presented as means of three brain sections. Abbreviations are listed in Fig. 1.
Brain Region | SERT +/+ | SERT +/- | SERT -/- | ||
|---|---|---|---|---|---|
| nCi/mg tissue | |||||
| [3H]AFM Binding | |||||
| CA1 | 0.92 | 0.62 | 0.04 | ||
| PH | 2.07 | 0.98 | -0.02 | ||
| LPTh | 1.13 | 0.73 | -0.02 | ||
| PV | 1.40 | 0.72 | -0.14 | ||
| CTX | 0.42 | 0.32 | 0.05 | ||
| DR (MB) | 3.45 | 1.29 | 0.00 | ||
| MR | 1.48 | 0.71 | 0.00 | ||
| CL | 2.32 | 1.39 | 0.04 | ||
| DR (cer) | 3.19 | 1.70 | -0.05 | ||
| [3H]-DASB Binding | |||||
| CA1 | 0.83 | 0.41 | 0.14 | ||
| PH | 1.61 | 0.89 | 0.09 | ||
| LPTh | 0.97 | 0.53 | -0.06 | ||
| PV | 1.50 | 0.62 | 0.13 | ||
| CTX | 0.56 | 0.21 | 0.01 | ||
| DR (MB) | 3.54 | 1.92 | 0.08 | ||
| MR | 1.78 | 0.62 | -0.02 | ||
| CL | 0.41 | 0.24 | 0.08 | ||
| DR (cer) | 1.10 | 0.64 | -0.11 | ||