TABLE 1

Effect of AG1478/PP2/MK886 on tumor size in nude mice (at day 21 after implantation of tumor cells)

Groups
Tumor Size (cm3)
Control 0.95 ± 0.22
Nicotine 3.82 ± 0.45*
Nicotine + AG1478 2.56 ± 0.31*#†
Nicotine + PP2 2.89 ± 0.29*#†
Nicotine + AG1478 + PP2 1.54 ± 0.21*#
Nicotine + MK886
2.08 ± 0.19*#†

  • ↵* p < 0.05 compared with the control group,

  • ↵# p < 0.05 compared with the nicotine group, and

  • ↵† p < 0.05 compared with the nicotine + AG1478 + PP2 group