TABLE 1

Pharmacokinetic properties of the four fluoroquinolones tested in our study


Fluoroquinolones Single Oral Dose

Plasma Cmax

Bioavailability
μM %
Pefloxacin, 500 mg 8.2-9.2 100
Levofloxacin, 500 mg 14 ≥99
Ofloxacin, 400 mg to 800 mg 14-30 95
Ciprofloxacin, 500 mg
5.6-6.9
56-77