TABLE 3

IC50 values for opioid effects on the contractility of electrically stimulated guinea pig ileum

The results summarized represent the mean ± S.E.M. from six to eight independent tissues.




μ

κ
nM
DPI-3290 3.4 ± 1.6 6.7 ± 1.6
BW373U86 150 ± 7 325 ± 9
Fentanyl 4.5 ± 1.4 146 ± 9
Morphine 51 ± 4 1370 ± 24
U69593
500 ± 15
4.2 ± 1.1