TABLE 5

Effects of BRL-52656 and SB-235863 on motor incoordination/ataxia

Compound
Peroral Dose
Performance Time
mg/kg s
Vehicle N/A 176 ± 12
BRL-52656 1.0 63 ± 13*
SB-235863
70
174 ± 8

  • N/A, not applicable.

  • ↵* P < 0.05 vs. rats injected with vehicle (Dunnett's test). The test procedures used and methods for analysis and expression of data are described under Materials and Methods. Data are the mean ± S.E.M. of results from six animals.