TABLE 1

Effects of water, LY235959, l-methadone, morphine, levorphanol, buprenorphine, and butorphanol on MSL over the five components of an experimental session

Values represent the mean and standard error for eight monkeys unless otherwise indicated.

	25-35 min	60-70 min	95-105 min	130-140 min	165-175 min
Water	0.07 (0.03)	0.08 (0.04)	0.09 (0.05)	0.09 (0.05)	0.10 (0.05)
LY235959
0.1 mg/kg	0.08 (0.03)	0.10 (0.03)	0.12 (0.04)	0.12 (0.05)	0.13 (0.03)
0.3 mg/kg	0.09 (0.02)	0.11 (0.04)	0.13 (0.04)	0.13 (0.03)	0.12 (0.03)
1.0 mg/kg	0.11 (0.05)	0.15 (0.08)	0.17 (0.08)	0.19 (0.08)	0.19 (0.08)
l-Methadone
0.1 mg/kg	0.12 (0.07)	0.13 (0.08)	0.07 (0.03)	0.08 (0.03)	0.08 (0.03)
0.3 mg/kg	0.19 (0.09)	0.20 (0.10)	0.14 (0.04)	0.15 (0.07)	0.14 (0.07)
0.56 mg/kg	0.79 (0.21)	0.89 (0.24)	0.67 (0.23)	0.41 (0.15)	0.33 (0.15)
Morphine
0.3 mg/kg	0.10 (0.06)	0.15 (0.09)	0.13 (0.08)	0.14 (0.08)	0.15 (0.09)
1.0 mg/kg	0.15 (0.08)	0.22 (0.13)	0.27 (0.15)	0.31 (0.17)	0.31 (0.19)
3.0 mg/kg	0.96 (0.26)	1.55 (0.20)	1.48 (0.25)^{n = 4}	1.25 (0.28)^{n = 2}	1.30 (0.00)^{n = 1}
Levorphanol
0.1 mg/kg	0.12 (0.07)	0.18 (0.13)	0.24 (0.19)	0.12 (0.08)	0.20 (0.16)
0.3 mg/kg	0.73 (0.24)	0.93 (0.26)	0.82 (0.22)	0.62 (0.19)	0.44 (0.17)
1.0 mg/kg	1.73 (0.06)^{n = 6}	1.80 (0.00)^{n = 5}	1.80 (0.00)^{n = 4}	1.80 (0.00)^{n = 2}	1.80 (0.00)^{n = 1}
Buprenorphine
0.01 mg/kg	0.16 (0.08)	0.23 (0.11)	0.19 (0.08)	0.17 (0.07)	0.15 (0.06)
0.03 mg/kg	0.21 (0.09)	0.49 (0.22)	0.38 (0.16)	0.28 (0.10)	0.25 (0.09)
0.1 mg/kg	0.81 (0.25)	1.01 (0.27)	0.86 (0.24)	0.73 (0.23)	0.60 (0.22)
Butorphanol
1.0 mg/kg	0.28 (0.09)	0.29 (0.09)	0.36 (0.13)	0.37 (0.13)	0.44 (0.15)
3.0 mg/kg	0.52 (0.18)	0.50 (0.18)	0.57 (0.20)	0.43 (0.18)	0.39 (0.16)
10.0 mg/kg	1.53 (0.27)	0.56 (0.20)	0.34 (0.09)	0.26 (0.07)	0.28 (0.10)