Effect of dexamethasone on epithelial cell apoptosis at the ulcer margin on day 4 and day 7 after ulcer induction
Field 1 means at the ulcer margin; fields 2 and 3 are the areas away from the ulcer margin to the adjacent normal mucosa. Values are means ± S.E.M. of 8 to 12 rats per group.
Number of Apoptosis Cells/mm2 | |||||
|---|---|---|---|---|---|
| Field 1 | Field 2 | Field 3 | |||
| Normal | 2.2 ± 0.7 | ||||
| Day 4 | |||||
| Control | 3.0 ± 0.7 | 2.7 ± 0.5 | 2.5 ± 0.6 | ||
| Dexamethasone 0.1 mg/kg | 2.6 ± 0.3 | 2.1 ± 0.2 | 1.7 ± 0.2 | ||
| Dexamethasone 0.2 mg/kg | 1.8 ± 0.3 | 1.8 ± 0.3 | 1.8 ± 0.3 | ||
| Day 7 | |||||
| Control | 4.3 ± 0.7† | 3.2 ± 0.6 | 3.0 ± 0.5 | ||
| Dexamethasone 0.1 mg/kg | 3.4 ± 0.4 | 2.7 ± 0.6 | 2.8 ± 0.6 | ||
| Dexamethasone 0.2 mg/kg | 3.0 ± 0.7 | 3.2 ± 0.8 | 2.6 ± 0.6 | ||
↵† p < 0.05 when compared with the normal group.