Concentration values for amiodarone and desethylamiodarone in the plasma and the heart mitochondria of rats measured by high-performance liquid chromatography 30 min after the i.v. administration of either 20 mg/kg amiodarone or desethylamiodarone
Results are expressed as mean ± S.E.M. (n = 3).
Plasma | Heart Mitochondria | |
|---|---|---|
| μg/ml ± S.E.M. | μg/mg ± S.E.M. | |
| Amiodarone | 4.1 ± 0.8 | 2.42 ± 0.29 |
| Desethylamiodarone | 4.3 ± 4.2 | 2.69 ± 0.28 |