LPS (10 mg/kg) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
VEH (1.0 ml/kg) | EDA (0.3 mg/kg) | EDA (1.5 mg/kg) | EDA (3.0 mg/kg) | EDA (6.0 mg/kg) | EDA (12. mg/kg) | ||||||
Mortality (%) | 100 | 100 | 50* | 0** | 0** | 33# |
VEH, saline.
↵* P < 0.05 compared with control rats given saline vehicle ** P < 0.01 compared with rats given saline vehicle; #P < 0.05 compared with rats given 6.0 mg/kg edaravone by Fisher's exact test.