TABLE 4

Baseline values of vehicle (n = 19), naratriptan (n = 7), rizatriptan (n = 7), and sumatriptan (n = 7) groups on hemodynamic parameters in the anesthetized pig

Data are means ± S.E.M.


Treatment

MAP

HR

SVR

TCVR

LADVR
mm Hg bpm mm Hg/l/min mm Hg/ml/min mm Hg/ml/min
Vehicle (n = 19) 89 ± 4 130 ± 6 57 ± 5 0.62 ± 0.05 3.1 ± 0.4
Naratriptan (n = 7) 94 ± 4 134 ± 10 62 ± 6 0.63 ± 0.08 4.0 ± 0.6
Rizatriptan (n = 7) 95 ± 3 132 ± 9 52 ± 3 0.39 ± 0.04* 3.3 ± 1.1
Sumatriptan (n = 7)
84 ± 5
122 ± 10
55 ± 7
0.63 ± 0.06
3.9 ± 0.6
  • bpm, beats per minute.

  • * P < 0.05 versus vehicle group assessed by one-way ANOVA followed by Dunnett's test.