Baseline values of MAP (mm Hg), heart rate (HR, beats per minute), MAP variability (SDMAP, mm Hg), SDRR (milliseconds), and (rMSSD) (milliseconds) in ethanol and pair-fed control SHRs before clonidine or saline administration
Values are means ± S.E.M. of four observations.
Parameter | Control | Ethanol 2.5% | Ethanol 5% | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Presaline | Preclonidine | Presaline | Preclonidine | Presaline | Preclonidine | ||||
| MAP | 156.7 ± 4.6 | 156.9 ± 2.9 | 142.8 ± 3.7* | 141.9 ± 2.4* | 124.8 ± 1.2* | 124.6 ± 1.1* | |||
| HR | 313.6 ± 3.1 | 310.8 ± 9.7 | 305.5 ± 2.9 | 319.8 ± 4.7 | 306.4 ± 3.1 | 315.4 ± 3.0 | |||
| SDMAP | 13.5 ± 1.1 | 14.1 ± 1.5 | 11.9 ± 0.7 | 11.9 ± 0.7 | 7.4 ± 1.5* | 9.1 ± 0.9* | |||
| SDRR | 19.8 ± 2.6 | 17.3 ± 1.7 | 17.4 ± 2.2 | 17.2 ± 1.1 | 15.2 ± 2.2 | 14.4 ± 1.5 | |||
| rMSSD | 9.3 ± 1.0 | 8.4 ± 0.7 | 9.2 ± 0.9 | 8.7 ± 0.8 | 7.1 ± 0.7 | 7.5 ± 1.1 | |||
↵* P < 0.05 versus corresponding control values.