TABLE 2

Effects of LAAM and norLAAM on oxygen delivery, transfer, and consumption during the 4-h experimental period relative to the initial 2-h control period (no opiates)

Each value represents the mean of at least six placentas ± S.D. The values for the initial 2-h control period were set as 100%.



O2 Delivery

O2 Transfer

O2 Consumption

Experimental Period
Percentage of Control Period
Experimental Period
Percentage of Control Period
Experimental Period
Percentage of Control Period
ml/min·kg ml/min·kg ml/min·kg
LAAM
    60 min 12.51 ± 4.56 96 0.405 ± 0.11 107 4.74 ± 2.67 88
    120 min 13.17 ± 2.49 101 0.389 ± 0.16 103 4.96 ± 0.68 91
    180 min 12.55 ± 3.21 96 0.354 ± 0.02 94 5.27 ± 1.45 97
    240 min 13.78 ± 3.39 106 0.413 ± 0.01 109 5.48 ± 2.57 101
norLAAM
    60 min 12.41 ± 5.25 97 0.450 ± 0.21 88 3.44 ± 1.13 75
    120 min 13.16 ± 5051 103 0.364 ± 0.22 71 3.88 ± 1.75 84
    180 min 12.70 ± 4.16 99 0.482 ± 0.21 94 3.47 ± 1.25 75
    240 min
12.17 ± 4.01
95
0.468 ± 0.10
91
3.15 ± 1.69
68