Peptide sequences used in these studies
| The property of peptide as substrate or inhibitor (or neither) is indicated. S1 and S2 are marked bold in peptide substrate 1. Replacement of S1 in other peptides is marked bold. S(p) represents phosphorylated serine. | ||||||||
|---|---|---|---|---|---|---|---|---|
| Peptide | Length | Substrate | Inhibitor | Comments | ||||
| 1. KRREILS1RRPS2(p)YR | 13 | + | — | Derived from CREB | ||||
| 2. ILSRRPS(p)YR | 9 | + | p9CREB | |||||
| 3. ILSRRPEYR | 9 | — | — | |||||
| 4. ILSRRPSYR | 9 | — | — | |||||
| 5. KRREILARRPS(p)YR | 13 | — | + | Hz13 | ||||
| 6. ILARRPS(p)YR | 10 | — | —a | |||||
| 7. KEEPPSPPQS(p)P | 11 | + | — | Derived from heat shock factor-1 | ||||
| 8. KEEPPAPPQS(p)P | 11 | — | + | pAHSF | ||||
| 9. KEAPPAPPQS(p)P | 11 | — | + | L803 | ||||
| 10. KEEPPAPPQSP | 11 | — | — | |||||
| 11. KEEPPAPPQEP | 11 | — | — | |||||
| 12. PAPPQS(p)P | 7 | — | —a | |||||
| 13. EPPAPRRE | 8 | — | — | |||||
| 14. EPPAPR | 6 | — | — |
| ||||
↵ a Weak inhibition (IC50 > 800 μM).