TABLE 1

Semiquantitative evaluation of tubular histological lesions

The grading system used for classifying tubular lesions is described under Material and Methods. Data are mean ± S.E.M. Histopathological classification is described under Materials and Methods.


Group

n

Histopathological Classification

Average Score
0
+1
+2
+3
Control 7 6 1 0 0 0.1 ± 0.1
Cisplatin 7 0 0 2 5 2.7 ± 0.2a
Cisplatin + Ed (1) 7 0 1 3 3 2.3 ± 0.3a, b
Cisplatin + Ed (5)
7
0
3
3
1
1.7 ± 0.3a, b
  • Ed (1), edarabone 1 mg/kg; Ed (5), edarabone 5 mg/kg.

  • a P < 0.05 versus control group

  • b P < 0.05 versus cisplatin group