Kinetic constants for the inactivation of mouse, rat, and human NQO1 by MMC
| Inactivation kinetics were calculated from the Kitz and Wilson plot shown in Fig. 4, as described under Materials and Methods. | ||||
|---|---|---|---|---|
| kinact | KI | |||
| min-1 | μM | |||
| Mouse | 0.142 | 83.2 | ||
| Rat | 0.0303 | 25.4 | ||
| Human | 0.169 | 64.8 | ||