Table 1

[11C]Befloxatone distribution in baboon's brain

Brain StructureUptake ± Standard DeviationDV ± Standard Deviation
%ID/100ml ml/g
Putamen1.79  ± 0.08122.4  ± 3.31
Caudate nucleus1.52  ± 0.00819.0  ± 4.10
Thalamus1.66  ± 0.06220.2  ± 3.93
Pons1.67  ± 0.15016.0  ± 3.60
Occipital cortex1.53  ± 0.21019.0  ± 1.85
Frontal cortex1.53  ± 0.24023.0  ± 2.13
Temporal cortex1.48  ± 0.25121.5  ± 3.20
Cerebellum1.07  ± 0.0509.7  ± 0.94
White matter0.91  ± 0.21411.0  ± 0.42

Comparison of [11C]befloxatone uptake obtained 30 min after i.v. administration and DV determined on the two hours experiments (n = 2). Uptake values are expressed in percent of injected dose per 100 ml of tissue. Values are mean and standard deviation.