Table 1

Chlorpyrifos dosing and testing protocols

Group	Dose	n	Exposure Period	Measurements/Testing Procedures
	mg/kg
1	0.0	12	24 h	→ Plasma cholinesterase
2	2.5	3	24 h	→ Plasma cholinesterase
3	10.0	4	24 h	→ Plasma cholinesterase
4	50.0	6	24 h	→ Plasma cholinesterase
5	100.0	6	24 h	→ Plasma cholinesterase
6	0.0	16	14 days	→ Weight, rearing and sniffing → 1-day drug washout → water maze → axonal transport
7	2.5	10	14 days	→ Weight, rearing and sniffing → 1-day drug washout → water maze → axonal transport
8	10.0	10	14 days	→ Weight, rearing and sniffing → 1-day drug washout → water maze → axonal transport
9	18.0	10	14 days	→ Weight, rearing and sniffing → 1-day drug washout → water maze → axonal transport
10	25.0	8	14 days	→ Weight, rearing and sniffing → 1-day drug washout → water maze → axonal transport
11	0.0	10	14 days	→ Weight, rearing and sniffing → 14-day drug washout → water maze → axonal transport
12	25.0	10	14 days	→ Weight, rearing and sniffing → 14-day drug washout → water maze → axonal transport
13	0.0	6	38 days	→ Weight, grip strength
14	2.5	10	38 days	→ Weight, grip strength