Changes in GST activities toward NBD and EA in primary cultured rat hepatocytes maintained in culture in the presence of various concentrations of glucagon for 3 days
| NBD | EA | |
|---|---|---|
| % control | ||
| Control | 100 ± 11 | 100 ± 23 |
| 1 nM Glucagon | 90 ± 13 | 86 ± 13 |
| 20 nM Glucagon | 66 ± 7* | 85 ± 13 |
| 100 nM Glucagon | 45 ± 16* | 86 ± 13 |
Values are shown as a percentage of the level monitored in hepatocytes cultured in the absence of glucagon (control, 100 %). In control hepatocytes, mean specific activities toward NBD and EA were 54 ± 6 and 19 ± 4 nmol/min/mg of protein, respectively. Data are means ± SD of three preparations of cell lysates.
3-150 Significantly different than levels monitored in control hepatocytes, P < 0.05.