Table 2

Steady-state data for retrograde perfusion of benzoate in the present studies were compared with those for prograde perfusion at similar concentrations of benzoate (data from Schwab et al., 2001)2-a

RatLiverFlowHematocritParameters for Benzoate
CInE2-b
g g ml/s/g μM
Retrograde (n = 8)296  ± 911.1  ± 2.20.020  ± 0.0050.14  ± 0.00415–180.60  ± 0.09
Prograde (n = 7)325  ± 2911.8  ± 1.50.017  ± 0.0020.16  ± 0.01*10–1790.59  ± 0.19

  • 2-150 Different from retrograde, P < 0.05.

  • ↵2-a Data were mean ± S.D.

  • ↵2-b Steady-state extraction ratio.