Table 3

Effects of S-1 and S-4 on serum LH and FSH levels

	FSH	LH
	ng/ml	ng/ml
Normal Range	5.6–20	0.15–0.7
Treatment
None (intact)	7.1 ± 1.2	0.27 ± 0.08
None (castrated)	30 ± 3^I	5 ± 2^I
TP (mg/day)
0.1	26 ± 6^I	4 ± 4^I
0.3	23 ± 6^I	2 ± 1^I,C
0.5	30 ± 7^I	5 ± 2^I
0.75	22 ± 5^I,C	1.4 ± 0.7^I,C
1.0	24 ± 8^I	2 ± 1^I,C
S-1 (mg/day)
0.1	28 ± 7^I	5 ± 2^I
0.3	27 ± 5^I	3 ± 1^I
0.5	22 ± 3^I,C	1.7 ± 0.3^I,C,T
0.75	20 ± 5^I,C	1.0 ± 0.7^C
1	23 ± 3^I,C	1.6 ± 0.7^I,C
S-4 (mg/day)
0.1	27 ± 5^I	4 ± 1^I
0.3	26 ± 1^I	3.7 ± 0.9^I
0.5	26 ± 8^I	2.4 ± 0.9^I,C
0.75	31 ± 5^I,T	3 ± 1^I
34 ± 5^I,T	2.4 ± 0.4^I,C

I, C, and T: significantly different (p < 0.05) from intact, castrated, and corresponding dose rate of TP-treated animals, respectively, as analyzed by single-factor ANOVA.