Table 1

Effect of minoxidil on GFR, urine volume, and plasma electrolytes

	GFR	UV	PNa	PK	PMg	PCa
	ml/min/100 g	ml/min	mM/l
Control periods
Control	0.734 ± 0.04	0.011 ± 0.001	142.1 ± 1.20	4.15 ± 0.16	0.68 ± 0.03	2.24 ± 0.05
Minoxidil	0.762 ± 0.05	0.013 ± 0.002	143.0 ± 0.94	4.51 ± 0.20	0.68 ± 0.02	2.06 ± 0.03
Experimental periods
Vehicle	0.690 ± 0.02	0.019 ± 0.002	141.0 ± 0.43	4.12 ± 0.09	0.66 ± 0.02	2.17 ± 0.03
Minoxidil	0.584 ± 0.03^1-150	0.007 ± 0.0008^1-160	144.3 ± 1.33	4.44 ± 0.14	0.68 ± 0.01	2.10 ± 0.02

Values are means ± S.E. from eight animals of each group. Control periods are the mean of two collection periods before administration of minoxidil or vehicle; experimental periods are the mean of four collection periods after i.v. minoxidil or vehicle.

UV, urine volume; PNa, plasma Na⁺; PK, plasma K⁺; PMg, plasma Mg²⁺; PCa, plasma Ca²⁺.
↵1-150 Significant difference from control (P < 0.05).
↵1-160 P < 0.01.