Table 4

7-EFC kinetics of CYP2B6 mutants

P450	V_max^4-a	n	K_m,S₅₀^4-b
2B6dH	14		8.5
I209L	7.9		38
S294D	1.1		35
L363V	4.5	1.6	7.8
V367L	10	0.7	5.6
V477F	25		11

Values are the means of two independent experiments performed in duplicate and conducted as described under Materials and Methods.