Drug | Midazolam ED50 | Substitution 95% CL |
---|---|---|
mg/kg | ||
Benzodiazepine site | ||
Flunitrazepam | 0.04 | 0.02–0.06 |
Midazolam | 0.15 | 0.08–0.23 |
Abecarnil | 0.48 | 0.32–0.68 |
Neuroactive steroid site | ||
Androsterone | 26.64 | 14.18–42.39 |
Dihydroandrosterone | 57.601-a | 55.59–59.70 |
Epipregnanolone | 58.211-a | 55.06–61.49 |
Data are from at least three monkeys unless otherwise specified.
↵1-a Data were determined from two of three monkeys.