Table 3

Effect of SSR182289A and reference anti-thrombin agents on thrombin generation in human plasma

IC50
μM
SSR182289A0.15 ± 0.02
Melagatran0.02 ± 0.004
Heparin0.02 ± 0.02
Nadroparin0.3 ± 0.02
Hirudin0.02 ± 0.02

Values shown are mean values ± S.E.M. (n = 3).