Table 1

Comparison of the inhibitory effect of DPDPE on evoked responses of ascending dorsal horn neurons in normal and diabetic rats

StimulusEC50 of DPDPE (95% Confidence Limits)
NormalDiabeticDiabetic (Normalized)
μM
Touch1.08 (0.47–4.98)0.09 (0.04–0.19)0.23 (0.07–1.40)
Pressure1.06 (0.39–4.94)0.09 (0.05–0.19)0.21 (0.08–1.17)
Pinch1.09 (0.47–2.53)0.08 (0.04–0.16)0.24 (0.04–1.20)