Table 1

Comparison of the potencies of substituted amidoximes and ketoxime

Compounds
IC50 μM
CIBZA8.3 ± 3.1
NO2BZA8.9 ± 0.9
Benzamidoxime28.1 ± 8.6*
MXBZA35.5 ± 6.4*
CIBZA2.1 ± 0.4
HXBZA26.6 ± 1.21-160
CIBK7.7 ± 0.41-160

IC50 values are calculated from the data illustrated in Fig. 4, B and C (mean ± S.E.M. of n = 5 experiments). For statistical analysis, IC50 values were compared to the one of CIBZA, using unpaired Student's t test.

  •  * p < 0.05.

  • 1-160p < 0.01.