Table 1

Blockade of the BuTAC-induced increase in serum corticosterone concentrations in acetylcholine muscarinic M₄KO mice and WT mice

Treatment	Serum Corticosterone
	WT Mice		M₄ KO Mice
	Vehicle	BuTAC	Vehicle	BuTAC
	ng/ml
Vehicle	106.0 ± 17.8	511.6 ± 25.7^1-150	44.4 ± 16.9	469.7 ± 67.5^1-150
Scopolamine	130.5 ± 24.9	161.1 ± 57.2^1-159	123.1 ± 15.9	124.6 ± 53.4^1-159

Scopolamine (1 mg/kg s.c.) was administered 15 min before BuTAC (0.1 mg/kg s.c.). Mice were sacrificed 1 h after BuTAC. Means and standard errors for five mice per group are shown.

↵1-150 P ≤ 0.05 compared with vehicle control.
↵1-159 P ≤ 0.05 compared with BuTAC alone.