Table 1

Percentage amino acid identity of bH1 versus four sodium channel isoforms

IsoformNDIL1DIIL2DIIIL3DIVC
Nav1.5 (rH1)9295869780971009893
Nav1.5 (hH1)9295869581971009692
Nav1.2 (α2)567238774671907763
Nav1.4 (μ1)586741802980868071
  • rH1, rat heart (Swissprot P15389); hH1, human heart (SwissprotQ14524); α2, rat brain 2 (Swissprot P04775); μl, rat skeletal muscle (Swissprot P15390). N, amino terminus; DI to DIV, domains one to four; C, carboxy terminus; L1 to L3, intracellular loops linking the four domains.