Dose-response data for WIN 55212-2 and a combination of WIN 55212-2 + an inactive dose of dextromethorphan (10 mg/kg, i.m.) using the peak depression in body temperature (either 60 or 90 min)
| WIN 55212-2 | Effect1-150(Alone) | Effect (Combination) |
|---|---|---|
| mg/kg | ||
| 1 | 0 | 1.8 |
| 2.5 | 1.6 | 2.8 |
| 5 | 2.3 | 3.8 |
| 10 | 3.5 |
↵1-150 Value is the mean from at least 10 rats.