Effects of losartan, PD123319, and L-NAME on the Ang II-induced relaxation of rat anococcygeus muscle precontracted with bethanechol
| Compounds | pD2 | Emax (% Tone of Bethanechol) |
|---|---|---|
| Control | 6.30 ± 0.15 | 65.50 ± 5.87 |
| Losartan | 6.55 ± 0.27 | 59.20 ± 10.62 |
| PD123319 | 6.18 ± 0.05 | 94.50 ± 6.382-150 |
| L-NAME | 6.52 ± 0.28 | 100.50 ± 3.282-150 |
Values shown are means ± S.E.M., n = 4.
↵2-150 P < 0.05, one-way ANOVA, compared to control group.